Campbell-Falck D, Thomas T, Falck TM, et al. The intravenous use of coconut water. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. Store at room temperature away from light and moisture. Do not remove the medication from the blister pack until right before using. If the medication comes in a bottle, keep container tightly closed. Do not store in the bathroom. Keep all medications away from children and pets. osir.info pantozol
This product may affect your levels. Before using potassium or salt substitutes that contain potassium, consult your doctor or pharmacist. Angiotensin II receptor antagonists may be used as an alternative for those patients in whom an ACE inhibitor or ARNI is inappropriate. Do not crush, chew, or break a telmisartan tablet. Swallow it whole. Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy.
The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. American Stroke Association. Stroke. Too much sweating, diarrhea, or vomiting may cause you to feel lightheaded. Report prolonged diarrhea or vomiting to your doctor.
Risks of use during pregnancy. Metabolized in liver via conjugation to inactive metabolite. Keep Micardis tablets and all medicines out of the reach of children. Report any light-headedness or fainting to your doctor immediately. Your risk of light-headedness or fainting may be increased if you experience diarrhea, vomiting, excessive sweating; do not drink enough fluids; or are on a low-salt diet. If you have diabetes, do not use telmisartan together with any medication that contains aliskiren Amturnide, Tekturna, Tekamlo, Valturna. rosuvastatin
Micardis telmisartan is an II receptor used to treat . Micardis is sometimes given together with other blood pressure medications. Keep out of the reach of children. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Do not co-administer aliskiren with Micardis in patients with diabetes. Tiredness and may also occur. If any of these effects persist or worsen, tell your doctor or promptly.
Food and Drug Administration. FDA public health advisory: angiotensin-converting enzyme inhibitor ACE inhibitor drugs and pregnancy. From FDA website. FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Telmisartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control. Take this by with or without food as directed by your doctor, usually once daily. It is best to avoid taking this medication within 4 hours of your to avoid having to get up to urinate. Consult your doctor or if you have questions about your dosing schedule. This list is not complete. Other drugs may interact with telmisartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. You may also need to avoid taking hydrochlorothiazide and telmisartan with aliskiren if you have kidney disease. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. Upper respiratory tract infection, sinusitis, pharyngitis, back pain, diarrhea. Should not be used in these patients. Plasma concentration of angiotensin II and plasma renin activity PRA increased in a dose-dependent manner after single administration of telmisartan to healthy subjects and repeated administration to hypertensive patients. The once-daily administration of up to 80 mg telmisartan to healthy subjects did not influence plasma aldosterone concentrations. In multiple dose studies with hypertensive patients, there were no clinically significant changes in electrolytes serum potassium or sodium or in metabolic function including serum levels of cholesterol, triglycerides, HDL, LDL, glucose, or uric acid. Distributed into milk in rats; not known whether distributed into human milk. The antihypertensive effect of telmisartan is not influenced by patient age, gender, weight, or body mass index. Blood pressure response in black patients usually a low-renin population is noticeably less than that in Caucasian patients. This has been true for most, but not all, angiotensin II antagonists and ACE inhibitors. Kidney problems, which may get worse if you already have kidney disease. You may have changes in your kidney test results, and you may need a lower dose of Micardis tablets. Do not stop taking any medications without consulting your healthcare provider. atorvastatin
Please refer to the for information on shortages of one or more of these preparations. Patients with severely reduced kidney function should receive a lower starting dose of 20 mg once a day. Patients with mild or moderately reduced liver function should not receive doses higher than 40 mg a day. How does Micardis work? Side effects with Micardis are not common. If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Smith DHG, Neutel JM, Morgenstern P. Once-daily telmisartan compared with enalapril in the treatment of hypertension. Adv Ther. Take Micardis HCT by mouth with or without food. Pfeffer MA, Swedberg K, Granger CB et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. Such potential risks occur throughout pregnancy, especially during the second and third trimesters.
If you have diabetes, do not use hydrochlorothiazide and telmisartan together with any medication that contains aliskiren Amturnide, Tekturna, Tekamlo, Valturna. Web MD. I am glad I am not the only one with these problems. The mean duration of follow up was 4 years and 8 months. The population studied was 57% male, 62% Caucasian, 21% Asian, and 60% were 65 years of age or older. Baseline therapy included acetylsalicylic acid 75% lipid lowering agents 58% beta-blockers 58% calcium channel blockers 41% nitrates 34% and diuretics 33%. You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Taler SJ, Agarwal R, Bakris GL et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD. Am J Kidney Dis. ACE inhibitor or angiotensin II receptor antagonist therapy. When telmisartan is used in fixed combination with amlodipine or hydrochlorothiazide, advise patients of important precautionary information about the concomitant agent. American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. Initially, 40 mg once daily in adults without intravascular volume depletion. Stangier J, Su CPF, Schöndorfer G et al. Pharmacokinetics and safety of intravenous and oral telmisartan 20 mg and 120 mg in subjects with hepatic impairment compared with healthy volunteers. J Clin Pharmacol. ceftin brand name price
It is not known whether hydrochlorothiazide and telmisartan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medication. Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure JNC V. Arch Intern Med. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Hyperkalemia may occur in patients on ARBs, particularly in patients with advanced renal impairment, heart failure, on renal replacement therapy, or on potassium supplements, potassium-sparing diuretics, potassium-containing salt substitutes or other drugs that increase potassium levels. Consider periodic determinations of serum electrolytes to detect possible electrolyte imbalances, particularly in patients at risk. Digoxin: When Micardis was co-administered with digoxin, median increases in digoxin peak plasma concentration 49% and in trough concentration 20% were observed. Therefore, monitor digoxin levels when initiating, adjusting, and discontinuing telmisartan for the purpose of keeping the digoxin level within the therapeutic range. Telmisartan belongs to a class of drugs called angiotensin receptor blockers ARBs. It works by relaxing vessels so can flow more easily. Hydrochlorothiazide is a "water pill" . It increases the amount of urine you make, especially when you first start the medication. It also helps to relax the blood vessels so that blood can flow more easily. Ask your health care provider any questions you may have about how to use Micardis HCT. Biphasic; terminal half-life is approximately 24 hours. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Have your checked regularly while taking this medication. Learn how to monitor your own pressure at home, and share the results with your doctor. Treatment of essential hypertension in adults. Crosses the placenta and is distributed in the fetus in animals. JATOS Study Group. Principal results of the Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients JATOS. Hypertens Res.
Some MEDICINES MAY INTERACT with Micardis HCT. Micardis was compared with ramipril another medicine to prevent cardiovascular problems and with the combination of both medicines. The main measure of effectiveness was the reduction in the number of patients who died or were admitted to hospital, or who had a heart attack or stroke. The patients were followed up for an average of four and a half years. What benefit has Micardis shown during the studies? Food and Drug Administration. FDA drug safety communication: ongoing safety review of the angiotensin receptor blockers and cancer. Rockville, MD; 2010 Jul 15. From FDA website. Keep each tablet in its blister pack until you are ready to take it. Tear or cut the blister apart from the rest of the package and peel back the paper liner. Do not remove Micardis tablets from blisters until right before you take them. What is High Blood Pressure Hypertension? Can cause fetal and neonatal morbidity and death when administered to a pregnant woman. a See Boxed Warning. Manufacturers state fixed-combination preparation should not be used for initial antihypertensive therapy. Micardis either alone or in combination with hydrochlorothiazide. Various doses of Micardis were compared with placebo a dummy treatment and with other medicines for hypertension atenolol, lisinopril, enalapril and amlodipine. The main measure of effectiveness was the reduction in diastolic blood pressure the blood pressure measured between two heartbeats. It is not known if Micardis passes into your breast milk. You and your doctor should decide if you will take Micardis tablets or breast-feed. You should not do both. Talk with your doctor about the best way to feed your baby if you take Micardis tablets. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Check with your pharmacist about how to dispose of unused medicine. cost of zocor duo
Some people take it to help reduce the effects certain medicines can have on the heart, muscles, and other organs. In rare cases, hydrochlorothiazide and telmisartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Micardis is available as white or off-white, uncoated tablets containing telmisartan 20 mg, 40 mg, or 80 mg. Tablets are marked with the BOEHRINGER INGELHEIM logo on one side, and on the other side, with either 50H, 51H, or 52H for the 20 mg, 40 mg, and 80 mg strengths, respectively. Micardis is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including the class to which this drug principally belongs. Izzo JL, Levy D, Black HR. Importance of systolic blood pressure in older Americans. Hypertension. Plasma concentrations of telmisartan are generally 2 to 3 times higher in females than in males. In clinical trials, however, no significant increases in blood pressure response or in the incidence of orthostatic hypotension were found in women. No dosage adjustment is necessary. Camargo AA, Fagundes Neto U. Intestinal transport of coconut water sodium and glucose in rats "in vivo". Tell your doctor if your condition does not improve or if it worsens such as your blood pressure readings remain high or increase. Call your doctor right away if you get any of the symptoms listed above. ONTARGET only, macro- or microalbuminuria stroke 16% peripheral vascular disease 13% or transient ischemic attack 4%. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial ALLHAT. JAMA. Food slightly reduces the bioavailability of telmisartan, with a reduction in the area under the plasma concentration-time curve AUC of about 6% with the 40 mg tablet and about 20% after a 160 mg dose. The absolute bioavailability of telmisartan is dose dependent. At 40 and 160 mg the bioavailability was 42% and 58%, respectively. The pharmacokinetics of orally administered telmisartan are nonlinear over the dose range 20 to 160 mg, with greater than proportional increases of plasma concentrations C max and AUC with increasing doses. Telmisartan shows bi-exponential decay kinetics with a terminal elimination half life of approximately 24 hours. Trough plasma concentrations of telmisartan with once daily dosing are about 10% to 25% of peak plasma concentrations. How should I take Micardis tablets? This drug may also be used to treat heart failure and to help protect the kidneys from damage due to diabetes.
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Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly. Read the Patient Information Leaflet if available from your pharmacist before you start taking telmisartan and each time you get a refill. If you have any questions, ask your doctor or pharmacist. buy cheapest inderal mastercard otc
All medicines may cause side effects, but many people have no, or minor, side effects. FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Hydrochlorothiazide and telmisartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
The information contained in the Truven Health Micromedex products as delivered by Drugs. Know the medicines you take. Keep a list of them and show it to your doctor or pharmacist when you get a new medicine. For patients with diabetes, if you are taking Micardis you should not take aliskiren. buy now cheapest clopidogrel canada
Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. American Diabetes Association. Standards of medical care in diabetes--2014. Diabetes Care. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.